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Associations between DSM-IV mental disorders and onset of self-reported peptic ulcer in the World Mental Health Surveys

dc.creatorScott, Kate M.
dc.creatorAlonso, Jordi
dc.creatorDe Jonge, Peter
dc.creatorViana, Maria Carmen
dc.creatorLiu, Zhaorui
dc.creatorO’Neill, Siobhan
dc.creatorAguilar-Gaxiola, Sergio
dc.creatorBruffaerts, Ronny
dc.creatorCaldas-de-Almeida, Jose Miguel
dc.creatorStein, Dan J.
dc.creatorAngermeyer, Matthias
dc.creatorBenjet, Corina
dc.creatorDe Girolamo, Giovanni
dc.creatorFiruleasa,  Ingrid-Laura
dc.creatorKiejna, Andrzej
dc.creatorKovess-Masfety, Viviane
dc.creatorLevinson, Daphna
dc.creatorNakane, Yoshibumi
dc.creatorPiazza, Marina
dc.creatorPosada-Villa, José A.
dc.creatorSalih Khalaf, Mohammad
dc.creatorLim, Carmen C. W.
dc.creatorKessler, Ronald C.
dc.date.accessioned2017-06-29T03:42:02Z
dc.date.available2017-06-29T03:42:02Z
dc.date.issued2013es_ES
dc.identifier2560es_ES
dc.identifier.issn0022-3999es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4409
dc.identifier.urihttps://doi.org/10.1016/j.jpsychores.2013.04.007es_ES
dc.description.abstractes_ES
dc.language.isoenges_ES
dc.publisheres_ES
dc.relation75(2) 121-127p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.subject.meshAdultes_ES
dc.subject.meshAge of Onsetes_ES
dc.subject.meshAgedes_ES
dc.subject.meshAged, 80 and overes_ES
dc.subject.meshComorbidityes_ES
dc.subject.meshDiagnostic and Statistical Manual of Mental Disorderses_ES
dc.subject.meshFemalees_ES
dc.subject.meshHealth Surveyses_ES
dc.subject.meshHumanses_ES
dc.subject.meshLife Change Eventses_ES
dc.subject.meshMalees_ES
dc.subject.meshMental Disorders/complicationses_ES
dc.subject.meshMental Disorders/diagnosises_ES
dc.subject.meshMental Disorders/epidemiologyes_ES
dc.subject.meshMiddle Agedes_ES
dc.subject.meshPeptic Ulcer/diagnosises_ES
dc.subject.meshPeptic Ulcer/epidemiologyes_ES
dc.subject.meshPeptic Ulcer/etiologyes_ES
dc.subject.meshPrevalencees_ES
dc.subject.meshProspective Studieses_ES
dc.titleAssociations between DSM-IV mental disorders and onset of self-reported peptic ulcer in the World Mental Health Surveyses_ES
dc.title.alternativees_ES
dc.typeartículoes_ES
dc.contributor.affiliationCorrespondence to: Kate M. Scott, PhD, Department of Psychological Medicine, Otago University, PO Box 913, Dunedin, New Zealand (kate.scott@otago.ac.nz); 64 3 4747007 ext 7369 (voice); 64 3 4747934 (fax)es_ES
dc.contributor.emailkate.scott@otago.ac.nzes_ES
dc.relation.jnabreviadoJ PSYCHOSOM RESes_ES
dc.relation.journalJournal of psychosomatic researches_ES
dc.identifier.placeInglaterraes_ES
dc.date.published2013es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.identifier.eissn1879-1360es_ES
dc.identifier.doi10.1016/j.jpsychores.2013.04.007es_ES
dc.description.monthAgoes_ES
dc.description.abstractotrodiomaObjective—Recent research demonstrating concurrent associations between mental disorders and peptic ulcers has renewed interest in links between psychological factors and ulcers. However, little is known about associations between temporally prior mental disorders and subsequent ulcer onset. Nor has the potentially confounding role of childhood adversities been explored. The objective of this study was to examine associations between a wide range of temporally prior DSM-IV mental disorders and subsequent onset of ulcer, without and with adjustment for mental disorder comorbidity and childhood adversities. Methods—Face-to-face household surveys conducted in 19 countries (n=52,095; person years=2,096,486).The Composite International Diagnostic Interview retrospectively assessed lifetime prevalence and age at onset of 16 DSM-IV mental disorders. Peptic ulcer onset was assessed in the same interview by self-report of physician’s diagnosis and year of diagnosis. Survival analyses estimated associations between first onset of mental disorders and subsequent ulcer onset. Results—After comorbidity and sociodemographic adjustment, depression, social phobia, specific phobia, post-traumatic stress disorder, intermittent explosive disorder, alcohol and drug abuse disorders were significantly associated with ulcer onset (Ors 1.3-1.6). Increasing number of lifetime mental disorders was associated with ulcer onset in a dose-response fashion. These associations were only slightly attenuated by adjustment for childhood adversities. Conclusions—A wide range of mental disorders were linked with the self-report of subsequent peptic ulcer onset. These associations require confirmation in prospective designs, but are suggestive of a role for mental disorders in contributing to ulcer vulnerability, possibly through abnormalities in the physiological stress response associated with mental disorders.es_ES
dc.subject.meshmes_ES
dc.subject.kwes_ES
dc.subject.koMental disorderses_ES
dc.subject.koDepressiones_ES
dc.subject.koAnxietyes_ES
dc.subject.koAlcohol abuse and dependencees_ES
dc.subject.koPeptic ulceres_ES


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