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Association of Mental Disorders With Subsequent Chronic Physical Conditions:  World Mental Health Surveys From 17 Countries

dc.creatorScott, Kate M.
dc.creatorLim, Carmen
dc.creatorAl-Hamzawi, Ali
dc.creatorAlonso, Jordi
dc.creatorBruffaerts, Ronny
dc.creatorCaldas-de-Almeida, José Miguel
dc.creatorFlorescu, Silvia
dc.creatorDe Girolamo, Giovanni
dc.creatorHu, Chiyi
dc.creatorDe Jonge,  Peter
dc.creatorKawakami, Norito
dc.creatorMedina-Mora, Maria Elena
dc.creatorMoskalewicz, Jacek,  Navarro-Mateu, Fernando
dc.creatorO’Neil, Siobhan
dc.creatorPiazza, Marina
dc.creatorPosada-Villa, José
dc.creatorTorres, Yolanda
dc.creatorKessler, Ronald C.
dc.date.accessioned2017-06-29T03:41:57Z
dc.date.available2017-06-29T03:41:57Z
dc.date.issued2016es_ES
dc.identifier2557es_ES
dc.identifier.issn2168-622Xes_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4406
dc.identifier.urihttp://doi.org710.1001/jamapsychiatry.2015.2688es_ES
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333921/es_ES
dc.description.abstractes_ES
dc.language.isoenges_ES
dc.publisheres_ES
dc.relation73(2) 150-158p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.subject.meshes_ES
dc.titleAssociation of Mental Disorders With Subsequent Chronic Physical Conditions:  World Mental Health Surveys From 17 Countrieses_ES
dc.title.alternativees_ES
dc.typeartículoes_ES
dc.contributor.affiliationDepartment of Psychological Medicine, University of Otago, PO Box 913, Dunedin, New Zealandes_ES
dc.contributor.emailkate.scott@otago.ac.nzes_ES
dc.relation.jnabreviadoJAMA PSYCHIATRYes_ES
dc.relation.journalJAMA psychiatryes_ES
dc.identifier.placeEstados Unidoses_ES
dc.date.published2016es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.identifier.eissn2168-6238es_ES
dc.identifier.doi10.1001/jamapsychiatry.2015.2688es_ES
dc.description.monthes_ES
dc.description.abstractotrodiomaIMPORTANCE It is clear that mental disorders in treatment settings are associated with a higher incidence of chronic physical conditions, but whether this is true of mental disorders in the community, and how generalized (across a range of physical health outcomes) these associations are, is less clear. This information has important implications for mental health care and the primary prevention of chronic physical disease. OBJECTIVE To investigate associations of 16 temporally prior DSM-IV mental disorders with the subsequent onset or diagnosis of 10 chronic physical conditions. DESIGN, SETTING, AND PARTICIPANTS Eighteen face-to-face, cross-sectional household surveys of community-dwelling adults were conducted in 17 countries (47 609 individuals; 2 032 942 person-years) from January 1, 2001, to December 31, 2011. The Composite International Diagnostic Interview was used to retrospectively assess the lifetime prevalence and age at onset of DSM-IV–identified mental disorders. Data analysis was performed from January 3, 2012, to September 30, 2015. MAIN OUTCOMES AND MEASURES Lifetime history of physical conditions was ascertained via self-report of physician’s diagnosis and year of onset or diagnosis. Survival analyses estimated the associations of temporally prior first onset of mental disorders with subsequent onset or diagnosis of physical conditions. RESULTS Most associations between 16 mental disorders and subsequent onset or diagnosis of 10 physical conditions were statistically significant, with odds ratios (ORs) (95% CIs) ranging from 1.2 (1.0-1.5) to 3.6 (2.0-6.6). The associations were attenuated after adjustment for mental disorder comorbidity, but mood, anxiety, substance use, and impulse control disorders remained significantly associated with onset of between 7 and all 10 of the physical conditions (ORs [95% CIs] from 1.2 [1.1-1.3] to 2.0 [1.4-2.8]). An increasing number of mental disorders experienced over the life course was significantly associated with increasing odds of onset or diagnosis of all 10 types of physical conditions, with ORs (95% CIs) for 1 mental disorder ranging from 1.3 (1.1-1.6) to 1.8 (1.4-2.2) and ORs (95% CIs) for 5 or more mental disorders ranging from 1.9 (1.4-2.7) to 4.0 (2.5-6.5). In population-attributable risk estimates, specific mental disorders were associated with 1.5% to 13.3% of physical condition onsets. CONCLUSIONS AND RELEVANCE These findings suggest that mental disorders of all kinds are associated with an increased risk of onset of a wide range of chronic physical conditions. Current efforts to improve the physical health of individuals with mental disorders may be too narrowly focused on the small group with the most severe mental disorders. Interventions aimed at the primary prevention of chronic physical diseases should optimally be integrated into treatment of all mental disorders in primary and secondary care from early in the disorder course.es_ES
dc.subject.meshmes_ES
dc.subject.kwes_ES
dc.subject.koes_ES


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