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Age differences in the prevalence and comorbidity of DSM-IV major depressive episodes: Results from the WHO World Mental Health Survey Initiative

dc.creatorKessler, Ronald C.
dc.creatorBirnbaum, Howard
dc.creatorShahly, Victoria
dc.creatorBromet, Evelyn
dc.creatorHwang, Irving
dc.creatorMcLaughlin, Katie A.
dc.creatorSampson, Nancy
dc.creatorAndrade, Laura Helena
dc.creatorDe Girolamo, Giovanni
dc.creatorDemyttenaere, Koen
dc.creatorHaro, Josep Maria
dc.creatorKaram, Aimee N.
dc.creatorKostyuchenko, Stanislav
dc.creatorKovess, Viviane
dc.creatorLara, Carmen
dc.creatorLevinson, Daphna
dc.creatorMatschinger, Herbert
dc.creatorNakane, Yoshibumi
dc.creatorOakley Browne, Mark
dc.creatorOrmel, Johan
dc.creatorPosada-Villa, Jose
dc.creatorSagar, Rajesh
dc.creatorStein, Dan J.
dc.date.accessioned2017-06-29T03:41:11Z
dc.date.available2017-06-29T03:41:11Z
dc.date.issued2010es_ES
dc.identifier2522es_ES
dc.identifier.issn1091-4269es_ES
dc.identifier.urihttp://repositorio.inprf.gob.mx/handle/123456789/4371
dc.identifier.urihttps://doi.org/10.1002/da.20634es_ES
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139270/es_ES
dc.description.abstractes_ES
dc.language.isoenges_ES
dc.publisheres_ES
dc.relation27(4) 351-364p.es_ES
dc.relationversión del editores_ES
dc.rightsacceso cerradoes_ES
dc.subject.meshAdultes_ES
dc.subject.meshAge Factorses_ES
dc.subject.meshAgedes_ES
dc.subject.meshComorbidityes_ES
dc.subject.meshCross-Cultural Comparisones_ES
dc.subject.meshCross-Sectional Studieses_ES
dc.subject.meshDepressive Disorder, Major/diagnosises_ES
dc.subject.meshDepressive Disorder, Major/epidemiologyes_ES
dc.subject.meshDepressive Disorder, Major/psychologyes_ES
dc.subject.meshDeveloping Countrieses_ES
dc.subject.meshDiagnosis, Differentiales_ES
dc.subject.meshFemalees_ES
dc.subject.meshHealth Surveyses_ES
dc.subject.meshHumanses_ES
dc.subject.meshMalees_ES
dc.subject.meshMental Disorders/diagnosises_ES
dc.subject.meshMental Disorders/epidemiologyes_ES
dc.subject.meshMental Disorders/psychologyes_ES
dc.subject.meshMiddle Agedes_ES
dc.subject.meshSomatoform Disorders/diagnosises_ES
dc.subject.meshSomatoform Disorders/epidemiologyes_ES
dc.subject.meshSomatoform Disorders/psychologyes_ES
dc.subject.meshWorld Health Organizationes_ES
dc.subject.meshYoung Adultes_ES
dc.titleAge differences in the prevalence and comorbidity of DSM-IV major depressive episodes: Results from the WHO World Mental Health Survey Initiativees_ES
dc.title.alternativees_ES
dc.typeartículoes_ES
dc.contributor.affiliationDepartment of Health Care Policy, Harvard Medical School, Boston, Massachusettses_ES
dc.contributor.emailkessler@hcp.med.harvard.edues_ES
dc.relation.jnabreviadoDEPRESS ANXIETYes_ES
dc.relation.journalDepression and anxietyes_ES
dc.identifier.placeEstados Unidoses_ES
dc.date.published2010es_ES
dc.identifier.organizacionInstituto Nacional de Psiquiatría Ramón de la Fuente Muñizes_ES
dc.identifier.eissn1520-6394es_ES
dc.identifier.doi10.1002/da.20634es_ES
dc.description.monthAbres_ES
dc.description.abstractotrodiomaBACKGROUND: Although depression appears to decrease in late life, this could be due to misattribution of depressive symptoms to physical disorders that increase in late life. METHODS: We investigated this issue by studying age differences in co-morbidity of DSM-IV major depressive episodes (MDE) with chronic physical conditions in the WHO World Mental Health (WMH) surveys, a series of community epidemiological surveys of respondents in 10 developed countries (n=52,485) and 8 developing countries (n=37,265). MDE and other mental disorders were assessed with the Composite International Diagnostic Interview (CIDI). Organic exclusion rules were not used to avoid inappropriate exclusion of cases with physical co-morbidity. Physical conditions were assessed with a standard chronic conditions checklist. RESULTS: Twelve-month DSM-IV/CIDI MDE was significantly less prevalent among respondents ages 65+ than younger respondents in developed but not developing countries. Prevalence of co-morbid mental disorders generally either decreased or remained stable with age, while co-morbidity of MDE with mental disorders generally increased with age. Prevalence of physical conditions, in comparison, generally increased with age, while co-morbidity of MDE with physical conditions generally decreased with age. Depression treatment was lowest among the elderly in developed and developing countries. CONCLUSIONS: The weakening associations between MDE and physical conditions with increasing age argue against the suggestion that the low estimated prevalence of MDE among the elderly is due to increased confounding with physical disorders. Future study is needed to investigate processes that might lead to a decreasing impact of physical illness on depression among the elderly.es_ES
dc.subject.meshmes_ES
dc.subject.kwes_ES
dc.subject.koElderlyes_ES
dc.subject.koDepressiones_ES
dc.subject.koDisabilityes_ES
dc.subject.koComorbidityes_ES
dc.subject.koEpidemiologyes_ES


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